权威例句
Role of IRS-2 in insulin and cytokine signallingDisruption of IRS-2 causes type 2 diabetes in mice.IRS-1-mediated inhibition of insulin receptor tyrosine kinase activity in TNF-alpha- and obesity-induced insulin resistanceStructure of the insulin receptor substrate IRS-1 defines a unique signal transduction proteinDecreased IRS-2 and Increased SREBP-1c Lead to Mixed Insulin Resistance and Sensitivity in Livers of Lipodystrophic and ob/ob MiceEffects of free fatty acids on glucose transport and IRS-1–associated phosphatidylinositol 3-kinase activityThe TSC1-2 tumor suppressor controls insulin–PI3K signaling via regulation of IRS proteinsAlternative pathway of insulin signalling in mice with targeteddisruption of the IRS-1 geneAn IL-4 receptor region containing an insulin receptor motif is important for IL-4-mediated IRS-1 phosphorylation and cell growthMechanism by which fatty acids inhibit insulin activation of insulin receptor substrate-1 (IRS-1)-associated phosphatidylinositol 3-...