progeria

n.

早衰，早老，儿童的早衰症；

Progeria syndromes and ageing: what is the connection?
Hutchinson-Gilford progeria syndrome: review of the phenotype
Lamin a truncation in Hutchinson-Gilford progeria
Phenotype and Course of Hutchinson–Gilford Progeria Syndrome
A Human iPSC Model of Hutchinson Gilford Progeria Reveals Vascular Smooth Muscle and Mesenchymal Stem Cell Defects
Recapitulation of premature ageing with iPSCs from Hutchinson-Gilford progeria syndrome.
Progressive vascular smooth muscle cell defects in a mouse model of Hutchinson–Gilford progeria syndrome
A farnesyltransferase inhibitor improves disease phenotypes in mice with a Hutchinson-Gilford progeria syndrome mutation
Inhibiting farnesylation of progerin prevents the characteristic nuclear blebbing of Hutchinson-Gilford progeria syndrome
Accumulation of mutant lamin A causes progressive changes in nuclear architecture in Hutchinson鈥揋ilford progeria syndrome