two-hit hypothesis

释义

[医]二次突变假说；

Two-Hit Hypothesis
Two-Hit Hypothesis
Mechanisms of inactivation of E-cadherin in breast carcinoma: modification of the two-hit hypothesis of tumor suppressor gene.
Alzheimer disease, the two-hit hypothesis: an update.
Modeling the two-hit hypothesis for evaluating strategies to prevent organ injury after shock/resuscitation
Mechanisms of inactivation of PTCH1 gene in nevoid basal cell carcinoma syndrome: modification of the two-hit hypothesis
Redefining tumour suppressor genes: exceptions to the two-hit hypothesis
Alfred Knudson and his two-hit hypothesis
Alfred Knudson and his two-hit hypothesis. (Interview by Ezzie Hutchinson)
Retinoblastoma: From the Two-Hit Hypothesis to Targeted Chemotherapy