权威例句
Smad2 and Smad3 positively and negatively regulate TGF beta-dependent transcription through the forkhead DNA-binding protein FAST2MADR2 maps to 18q21 and encodes a TGFbeta-regulated MAD-related protein that is functionally mutated in colorectal carcinomaSmad2 Signaling in Extraembryonic Tissues Determines Anterior-Posterior Polarity of the Early Mouse EmbryoMADR2 is a substrate of the TGFbeta receptor and its phosphorylation is required for nuclear accumulation and signaling.MADR1, a MAD-related protein that functions in BMP2 signaling pathways.Targeted disruption in murine cells reveals variable requirement for Smad4 in transforming growth factor beta-related signalingThe winged-helix transcription factor HNF-3 beta is required for notochord development in the mouse embryo.Specific activation of Smad1 signaling pathways by the BMP7 type I receptor, ALK2Targeted Disruption in Murine Cells Reveals Variable Requirement for Smad4 in Transforming Growth Factor 尾-related SignalingSpecific activation of SMAD1 signaling pathways by the BMP7 type 1 receptor, ALK2