权威例句
Senescence and immortalization: role of telomeres and telomeraseImmortalization eliminates a roadblock during cellular reprogramming into iPS cellsImmortalization of hypothalamic GnRH neurons by genetically targeted tumorigenesis.Human papillomavirus immortalization and transformation functions.Cellular immortalization by a cDNA clone encoding the transformation-associated phosphoprotein p53.Induction of p16 during immortalization by HPV 16 and 18 and not during malignant transformationMyc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalization.Targeted disruption of the three Rb-related genes leads to loss of G(1) control and immortalizationDissociation among in vitro telomerase activity, telomere maintenance, and cellular immortalizationhEST2, the putative human telomerase catalytic subunit gene, is up-regulated in tumor cells and during immortalization.