权威例句
Isocitrate dehydrogenase 1 codon 132 mutation is an important prognostic biomarker in gliomas.Isocitrate Dehydrogenase 1 and 2 Mutations in Cancer: Alterations at a Crossroads of Cellular MetabolismProfiling the effects of isocitrate dehydrogenase 1 and 2 mutations on the cellular metabolomeMycobacterium tuberculosis isocitrate lyases 1 and 2 are jointly required for in vivo growth and virulence.Hypoxia promotes isocitrate dehydrogenase-dependent carboxylation of α-ketoglutarate to citrate to support cell growth and viabilityFrequent Mutation of Isocitrate Dehydrogenase (IDH)1 and IDH2 in Cholangiocarcinoma Identified Through Broad-Based Tumor GenotypingThe enzymatic mechanism of oxidation-redactions between malate or isocitrate and pyravate.Structures of human cytosolic NADP-dependent isocitrate dehydrogenase reveal a novel self-regulatory mechanism of activityPersistence of Mycobacterium tuberculosis in macrophages and micerequires the glyoxylate shunt enzyme isocitrate lyaseCancer-associated metabolite 2-hydroxyglutarate accumulates in acute myelogenous leukemia with isocitrate dehydrogenase 1 and 2 muta...