权威例句
Regulation of gene expression by SREBP and SCAP.Cholesterol feedback: from Schoenheimer's bottle to Scap's MELADLRegulated step in cholesterol feedback localized to budding of SCAP from ER membranes.Molecular regulation of SREBP function: the Insig-SCAP connection and isoform-specific modulation of lipid synthesis.Sterols Regulate Cycling of SREBP Cleavage-Activating Protein (SCAP) between Endoplasmic Reticulum and GolgiCholesterol Addition to ER Membranes Alters Conformation of SCAP, the SREBP Escort Protein that Regulates Cholesterol MetabolismCrucial step in cholesterol homeostasis: Sterols promote binding of SCAP to INSIG-I, a membrane protein that facilitates retention o...Crucial step in cholesterol homeostasis: sterols promote binding of SCAP to INSIG-1, a membrane protein that facilitates retention o...Compensatory increase in fatty acid synthesis in adipose tissue of mice with conditional deficiency of SCAP in liver.Cholesterol and 25-hydroxycholesterol inhibit activation of SREBPs by different mechanisms, both involving SCAP and Insigs.