scurfy

adj.

有皮屑的；

The Scurfy mutation of FoxP3 in the thymus stroma leads to defective thymopoiesis.
Disease in the scurfy (sf) mouse is associated with overexpression of cytokine genes
TGF-beta-induced Foxp3+ regulatory T cells rescue scurfy mice.
Cellular and molecular characterization of the scurfy mouse mutant.
The scurfy mouse mutant has previously unrecognized hematological abnormalities and resembles Wiskott-Aldrich syndrome.
Selective depletion of Foxp3+regulatory T cells induces a scurfy-like disease
Transplantation of T cell-mediated, lymphoreticular disease from the scurfy (sf) mouse.
Fatal lymphoreticular disease in the scurfy (sf) mouse requires T cells that mature in a sf thymic environment: potential model for ...
Lahl, K. et al. Selective depletion of Foxp3+ regulatory T cells induces a scurfy-like disease. J. Exp. Med. 204, 57-63
X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy.