AGM-1470

释义

[医](TNP-470)是一种人工合成的烟曲霉素衍生物，体内外具有强烈的抑制内皮细胞增殖和血管形成的作用，比烟曲霉素的作用大50倍，且毒副作用小。；

AGM-1470
Methionine aminopeptidase (type 2) is the common target for angiogenesis inhibitors AGM-1470 and ovalicin
Potent anti-angiogenic action of AGM-1470: comparison to the fumagillin parent.
Cytostatic inhibition of endothelial cell growth by the angiogenesis inhibitor TNP-470 (AGM-1470)
Angiogenesis inhibitor TNP-470 (AGM-1470) potently inhibits the tumor growth of hormone-independent human breast and prostate carcin...
Critical components of the female reproductive pathway are suppressed by the angiogenesis inhibitor AGM-1470
Suppression of collagen-induced arthritis using an angiogenesis inhibitor, AGM-1470, and a microtubule stabilizer, taxol
A fumagillin derivative angiogenesis inhibitor, AGM-1470, inhibits activation of cyclin-dependent kinases and phosphorylation of ret...
Suppression of arthritis and protection from bone destruction by treatment with TNP-470/AGM-1470 in a transgenic mouse model of rheu...
AGM-1470, a potent angiogenesis inhibitor, prevents the entry of normal but not transformed endothelial cells into the G1 phase of t...